podrias usar tablas anidadas, algo asi
<table width="100%" border="0" cellpadding="0" cellspacing="0">
<tr valign="top">
<td height="721"><table border="0" cellpadding="0" cellspacing="0" vspace="0">
<tr>
<td><img src="spacer.gif" width="16" height="1" border="0" alt=""></td>
<td><img src="spacer.gif" width="133" height="1" border="0" alt=""></td>
</tr>
<tr>
<td rowspan="6" valign="top"><img name="index_r2_c1" src="index_r2_c1.gif" width="16" height="521" border="0" alt=""></td>
<td rowspan="3" valign="top" nowrap><img src="index_r2_c2.gif" width="133" height="231"></td>
</tr>
<tr> </tr>
<tr> </tr>
<tr>
<td rowspan="3" valign="top" nowrap background="index_r5_c2.gif"><p align="center" class="Estilo2"> Noticias<br>
Sobre la película<br>
Personajes<br>
Desarrolladores<br>
Cast<br>
<img src="multimedia.gif" width="116" height="30"> <br>
Capturas<br>
Vídeos<br>
Fondos de pantalla<br>
Scans<br>
Miscelánea <br>
<img src="laweb.gif" width="116" height="30"><br>
Contacta<br>
Staff</p></td>
</tr>
<tr> </tr>
<tr> </tr>
<tr>
<td valign="top"> </td>
<td background="index_r8_c2.gif"> </td>
</tr>
</table></td>
<td><table border="0" cellpadding="0" cellspacing="0" vspace="0">
<tr>
<td><img src="spacer.gif" width="39" height="1" border="0" alt=""></td>
<td><img src="spacer.gif" width="508" height="1" border="0" alt=""></td>
<td><img src="spacer.gif" width="42" height="1" border="0" alt=""></td>
</tr>
<tr>
<td colspan="3"><img name="index_r2_c3" src="index_r2_c3.gif" width="589" height="177" border="0" alt=""></td>
</tr>
<tr>
<td colspan="3" background="index_r3_c3.gif"><div align="center"><strong><span class="Estilo1">Bienvenido a la página web de FF:AC Obsesion, tu web de Final Fantasy VII: AC en castellano. </span></strong> </div></td>
</tr>
<tr>
<td colspan="3" rowspan="2" valign="top"><p> </p>
<p> </p>
<p> </p>
<p> </p>
<p> </p>
<p> </p>
<p> </p>
<p> </p></td>
</tr>
<tr> </tr>
<tr>
<td rowspan="2"><img name="index_r6_c3" src="index_r6_c3.gif" width="39" height="61" border="0" alt=""></td>
<td colspan="2"><img name="index_r6_c4" src="index_r6_c4.gif" width="550" height="2" border="0" alt=""></td>
</tr>
<tr>
<td><p> </p></td>
<td><img name="index_r7_c5" src="index_r7_c5.gif" width="42" height="59" border="0" alt=""></td>
</tr>
<tr>
<td colspan="3" background="index_r8_c3.gif" class="Estilo1"><div align="center"><strong>Final Fantasy Advent Children Obsesion © 2005-2006 Todos los derechos reservados.</strong></div></td>
</tr>
</table></td>
<td><table border="0" cellpadding="0" cellspacing="0" vspace="0">
<tr>
<td><img src="spacer.gif" width="148" height="1" border="0" alt=""></td>
</tr>
<tr>
<td rowspan="3" valign="top" nowrap><img src="index_r2_c6.gif" width="148" height="231"></td>
</tr>
<tr> </tr>
<tr> </tr>
<tr>
<td rowspan="3" valign="top" background="index_r5_c6.gif"> </td>
</tr>
<tr> </tr>
<tr> </tr>
<tr>
<td background="index_r8_c6.gif"> </td>
</tr>
</table></td>
</tr>
</table>